PRP vs PRF: What’s the Difference?
PRP and PRF are two regenerative treatments commonly used in aesthetic medicine to support collagen production, skin rejuvenation, and healing. While they’re often discussed interchangeably, they are processed differently — and that difference can impact how they perform over time.
At Aster Aesthetics, we believe patient education is an important part of treatment planning. Understanding the difference between PRP and PRF helps patients make more informed decisions about their skin and regenerative treatment options.
What Is PRP?
PRP stands for Platelet-Rich Plasma.
PRP is created by drawing a small amount of your blood and spinning it in a centrifuge to separate concentrated platelets and growth factors from the rest of the blood components.
The final product has a more liquid consistency and delivers a quicker release of growth factors once injected or applied during treatment.
PRP is often used to:
- Support healing
- Stimulate collagen production
- Improve overall skin quality
- Complement microneedling and hair restoration treatments
Because PRP releases growth factors more rapidly, it tends to create a more immediate signaling response within the tissue.
What Is PRF?
PRF stands for Platelet-Rich Fibrin.
Like PRP, PRF also uses your own blood and regenerative growth factors. However, the processing method is different. PRF is spun at a lower speed and contains a fibrin matrix, creating more of a gel-like consistency.
This allows for a slower, more sustained release of growth factors over time.
PRF is also unique because it does not contain anticoagulants or additives, making it a more natural regenerative option.
PRF is commonly used for:
- Under-eye rejuvenation
- Skin rejuvenation
- Hair restoration
- Supporting collagen stimulation gradually over time
PRP vs PRF: The Main Difference
The biggest difference between PRP and PRF comes down to timing and delivery.
PRP:
- Faster release of growth factors
- Liquid consistency
- Shorter duration of regenerative activity
PRF:
- Slower, extended release
- Gel-like fibrin matrix
- Longer regenerative activity
Both treatments stimulate collagen and support tissue repair — they simply work on different timelines.
Why We Often Use PRF at Aster Aesthetics
At Aster Aesthetics, we frequently recommend PRF because of its gradual, sustained regenerative response and natural-looking results.
We especially love PRF for delicate areas such as the under eyes, where subtle improvement and collagen support are key.
Every patient is different, which is why treatment recommendations are always personalized based on anatomy, goals, timeline, and overall treatment plan.
Natural Results. Elevated Care.
Regenerative aesthetics continues to evolve, and treatments like PRP and PRF offer exciting options for patients looking to support skin quality and collagen naturally.
If you’re curious whether PRP or PRF may be right for you, we’d love to create a personalized treatment plan during your consultation.
We’re proud to care for patients in Salem, Keizer, and throughout Marion County, while welcoming patients from across the Willamette Valley. Our approach centers on natural, balanced results, with a strong focus on long-term skin health and integrity. Wherever you’re starting, we meet you there —creating personalized plans that evolve with you and deliver refined, intentional results
